U.S. shares lower at close of trade; Dow Jones Industrial Average down 0.56% – U.S. equities were lower at the close on Thursday, as losses in the , and sectors propelled shares lower.

At the close in NYSE, the lost 0.56% to hit a new 1-month low, while the index declined 1.13%, and the index fell 1.43%.

The biggest gainers of the session on the were UnitedHealth Group Incorporated (NYSE:), which rose 2.58% or 13.14 points to trade at 522.91 at the close. JPMorgan Chase & Co (NYSE:) added 1.51% or 1.75 points to end at 117.87 and Goldman Sachs Group Inc (NYSE:) was up 1.33% or 4.36 points to 331.62 in late trade.

Biggest losers included Salesforce Inc (NYSE:), which lost 3.43% or 5.50 points to trade at 154.78 in late trade. Microsoft Corporation (NASDAQ:) declined 2.71% or 6.84 points to end at 245.38 and Visa Inc Class A (NYSE:) shed 2.03% or 4.04 points to 195.37.

The top performers on the S&P 500 were Humana Inc (NYSE:) which rose 8.37% to 497.24, Wynn Resorts Limited (NASDAQ:) which was up 7.48% to settle at 65.23 and Paramount Global Class B (NASDAQ:) which gained 5.16% to close at 23.05.

The worst performers were Adobe Systems Incorporated (NASDAQ:) which was down 16.79% to 309.13 in late trade, Albemarle Corp (NYSE:) which lost 6.49% to settle at 286.75 and West Pharmaceutical Services Inc (NYSE:) which was down 5.88% to 273.73 at the close.

The top performers on the NASDAQ Composite were Heartbeam Inc (NASDAQ:) which rose 85.60% to 2.32, Neurobo Pharmaceuticals Inc (NASDAQ:) which was up 47.21% to settle at 24.82 and Nabriva Therapeutics AG (NASDAQ:) which gained 40.65% to close at 0.27.

The worst performers were Shuttle Pharmaceuticals Inc (NASDAQ:) which was down 55.65% to 16.63 in late trade, Eloxx Pharmaceuticals Inc (NASDAQ:) which lost 40.97% to settle at 0.22 and Color Star Technology Co Ltd (NASDAQ:) which was down 39.54% to 0.07 at the close.

Declining stocks outnumbered rising ones by 2194 to 935 and 113 ended unchanged; on the Nasdaq Stock Exchange, 1992 fell and 1758 advanced, while 265 ended unchanged on the New York Stock Exchange.

The , which measures the implied volatility of S&P 500 options, was up 0.42% to 26.27.

In commodities trading, Gold Futures for December delivery was down 2.08% or 35.55 to $1,673.55 a troy ounce. Meanwhile, Crude oil for delivery in October fell 3.84% or 3.40 to hit $85.08 a barrel, while the November Brent oil contract fell 3.55% or 3.34 to trade at $90.76 a barrel.

EUR/USD was unchanged 0.19% to 1.00, while USD/JPY rose 0.23% to 143.48.

The US Dollar Index Futures was up 0.06% at 109.44.

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